Topical tacrolimus as treatment of atopic dermatitis
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چکیده
منابع مشابه
Topical tacrolimus as treatment of atopic dermatitis
Atopic dermatitis (AD) is a common, chronic, relapsing, severely pruritic, eczematous skin disease. The mainstays of treatment for AD are topical tacrolimus and topical steroids. Tacrolimus, a calcineurin inhibitor, not only complements existing treatment options but also overcomes some of the drawbacks of topical steroid therapy when given topically and thus meets the long-term needs of patien...
متن کاملAtopic dermatitis: tacrolimus vs. topical corticosteroid use
Atopic dermatitis (AD), the dermatological manifestation of the atopic diathesis, has a variety of clinical presentations. It is a chronic and relapsing inflammatory disorder, requiring a multifaceted treatment approach. Topical corticosteroids are the backbone of therapy. However, concerns over adverse drug reactions associated with their long-term application limit their use. Tacrolimus, on t...
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Accessible online at: www.karger.com/journals/drm Today, there is ample scientific evidence for the clinical effectiveness, safety and patient comfort of tacrolimus ointment in the treatment of moderate to severe atopic dermatitis. Recent, well-documented reports on doubleblind, vehicle-controlled, randomized clinical studies encompass data from 419 adults [1] and 235 children [2] who were succ...
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Atopic dermatitis is a common problem affecting up to 10 percent of all children. The mainstays of therapy have been oral antihistamines, topical emollients, topical doxepin, and topical corticosteroids. Side effects associated with higher potency topical corticosteroids have limited their use in children and for facial areas. Tacrolimus (Protopic) is an immunosuppressive agent typically used s...
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particular, in the case of a family history of febrile episodes, the possibility of TRAPS should be considered if an aetiology of autoimmune or infectious nature is excluded. The discovery of three different mutations in a population as small as the Finnish, reinforces the notion that the extracellular domain of TNFRSF1A is prone to be mutated at the entire stretch of its cysteine-rich domains ...
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ژورنال
عنوان ژورنال: Clinical, Cosmetic and Investigational Dermatology
سال: 2009
ISSN: 1178-7015
DOI: 10.2147/ccid.s4122